Dr. Spence is excited to announce that he will be joining the the OU Department of Neurosurgery and will continue to see existing and new patients in a new office located at OU Medical Center.

OU Medical Center: Department of Neurosurgery 
(located in the OU Health-Harold Hamm Diabetes Center)
1000 N. Lincoln Blvd., Ste. 4000
Oklahoma City, OK 73104

New contact numbers are:
For clinical related question: 405-271-4912
Referral information fax: 405-271-3091
Nurse information fax: 405-271-7834

About Us

About Dr. Spence

Dr. Caple A. Spence is a Neurosurgeon who is an expert in Brain, Spine and Peripheral Nerve surgery. He specializes in the evaluation, management and treatment of surgical neurologic conditions including but not limited to brain tumors, cerebrovascular disease, spinal fractures, rheumatoid arthritis, trigeminal neuralgia, degenerative disc disease, spinal osteoarthritis, spinal stenosis, disc herniation, ankylosing spondylitis, tumors of the skull base and the pituitary gland, tumors of the spinal cord and the vertebrae, spinal deformity, adult scoliosis, failed back syndrome and infectious diseases of the brain and spine.

Dr. Spence received his undergraduate degree in 1991 from New York University, the largest private university in the United States. He went on to obtain his medical degree in 1995 from Mount Sinai School of Medicine where he developed his love of neurosurgery while learning from neurosurgical giants such as Leonard Malis, Kalmon Post and Chandra Sen. He then completed an Internship in General Surgery at George Washington University Medical Center. There he continued his 6 year neurosurgical training where he gained expertise in cranial and spinal microneurosurgery. Dr. Spence then completed a fellowship in Complex Reconstructive Spinal Surgery at the University of South Florida at Tampa General. He was appointed Assistant Professor of Neurosurgery following his fellowship. Dr. Spence was Co-founder and Co Director of the Iowa Spine and Brain Institute where he help form a multidisciplinary team to treat neurosurgical diseases. During his term there, ISBI became the most comprehensive center for the treatment of disease of the brain and spine in Northeast Iowa. He is board certified by the American Board of Neurological Surgeons and is a Fellow of the American Association of Neurological Surgeons.

For over 18 years, Dr. Spence has been active in medical education in a variety of capacities. His writings and scholarly activity has been published in books and peer reviewed journals. He has presented research at numerous scientific meetings and has given lectures widely. Dr. Spence has been an Advisory editor to The Spine Journal and served as a faculty member for the AANS Goodman Oral Board Preparation: Neurosurgery Review by Case Management course, which helps to prepare neurosurgeons for achieving board certification. He is a Fellow of the American College of Surgeons and a Fellow of the American Association of Neurological Surgeons. He is a member of multiple professional medical societies. These include:


Our Philosophy

Neurosurgical problems are frequently painful and can cause movement to be difficult or impossible. Often, neurological signs and symptoms can be puzzling and frustrating to understand. We all know how we would like to be taken care of when tragedy strikes, and that drives the philosophy of our staff. In our office, you will notice the warm, courteous reception the moment you open the door. Relax in our comfortable waiting area and have a beverage. Our compassion combined with knowledge and experience is evident as we perform a thorough medical and neurosurgical evaluation then develop a unique set of treatment options using a multi-specialty team approach. We provide a variety of non-surgical and surgical treatment options. Through open dialogue we reflect on the risks, benefits and alternatives of each option and assist patients in making their decisions. We encourage questions and the collaboration of family and close friends as part of the process.

Dr. Spence specializes in the evaluation and treatment of a variety of brain, spinal and peripheral nerve disorders. We use state-of-the-art technology in both diagnosis and treatment. Being fellowship-trained, Dr. Spence realizes the value of working in collaboration with a team including interventional neuro-radiologists, neurologists, vascular surgeons, neuro-otologists, endocrinologists, pain management specialists, critical care specialists, medical and radiation oncologists. By collaborating with these specialists, Dr. Spence and his colleagues are dedicated to providing the Oklahoma city area and surrounding communities with the highest quality of healthcare.

We offer treatment strategies utilizing minimally invasive techniques both in the brain and in the spine. These techniques are usually performed through very small incisions and allow for a rapid, less painful recovery.  We also excel in treating complex cranial disorders, reconstructing complex spinal deformities and doing revision spinal surgery.

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